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Factors contained in the human-derived mesenchymal stem cell culture supernatant

武本 重毅

The stem cell culture supernatant used in our clinic is obtained by culturing human-derived mesenchymal stem cells (those whose safety has been confirmed by testing for infectious diseases)

It contains exosomes (a type of extracellular endoplasmic reticulum) and cytokine (growth factor) abundantly.

 

TGF (Transforming Growth Factor)

Induction of mitogenic effect (DNA synthesis) and promotion of cell proliferation

Precursor of new bone, bone strengthening

Improvement of firmness and texture of the skin, whitening effect

 

IGF (insulin-like growth factor)

Stimulation of cell proliferation and differentiation

Bone regeneration, bone strengthening

Promote collagen fiber synthesis, skin repair, wrinkle improvement and firmness improvement

 

VEGF (vascular endothelial growth factor)

Promoting angiogenesis and cell activity

Promoting regeneration and repair of organs and tissues

Retention of elasticity, promoting skin repair, improvement of serious wrinkles

 

HGF (hepatocyte growth factor)

New generation, maintenance and remodeling of cell and tissue structures

Promoting regeneration and repair of organs and tissues

Promotion of skin metabolism and turnover

 

KGF (keratinocyte growth factor)

Promotion of epidermal turnover

Promoting regeneration and repair of organs and tissues

Turnover of old keratin, elimination of dullness

 

PDGF (platelet-derived growth factor)

Promoting stem cell mitosis and extracellular structure synthesis

Promoting regeneration and repair of systemic organs, tissues and cells

Promotion healing of skin scars, blemishes and allergies

 

bFGF (basic fibroblast growth factor)

Fibroblast growth promotion

Promoting repair of various soft tissue injuries

Whitening effect, removal of wrinkles and scars

 

Fibronectin (cell adhesion glycoprotein)

Maintaining elasticity of tendons and skin

Promoting regeneration and repair of organs and tissues

Maintaining strong skin tissue structure

 

Procollagen

Composition of important proteins, improvement of elasticity, improvement of wrinkles

Promoting regeneration and repair of organs and tissues

Maintenance of skin elasticity

 

and

 

It also has important functions to control of the immune system.

Author:

武本 重毅

聚楽内科クリニックの院長、医学博士。